BiQ: Weekly Recap for 10/10/26
It's been a while since I published a Weekly Recap. I felt that regular, daily updates via BiQ Chat would prove more helpful for members; however, since many BiQ members still haven't signed up for BiQ Chat, I will also try to provide regular updates via this email newsletter to keep non-chat members better up to date. Still, I strongly recommend members join BiQ Chat if at all possible by clicking here.
Members who follow along in the chat forum are probably aware that, over the past year, I've also been providing significant coverage of my non-biotech investing ideas. I feel recent technological innovations offer investors a once-in-a-lifetime opportunity across multiple industrial sectors. Although I remain committed to the biotech sector, and it remains a core focus at Biotech iQ, I also believe it's in investors' interest to follow what's happening across industries spanning technology, aerospace, space, defense, mining, energy, and precious metals. I have significant investments across these sectors, which I have been sharing with BiQ members through BiQ Chat.
While each sector is unique and requires a different analytical approach, my core methodology remains the same: identify opportunities the market is undervaluing through deep research, develop a long-term thesis, identify an attractive entry point, tune out the short-term volatility & noise, and remain invested as long as the thesis stays on track and the risk/reward looks attractive. This has served us very well for our biotech names, and is also working well for the non-biotech portfolio. BiQ members can view the current status and performance of the biotech and non-biotech portfolio by clicking here.
For now, my plan is to keep everything under one service, which I believe offers the most value to BiQ members. I may revisit this in the future if the information flow becomes too overwhelming. For now, the Biotech iQ Active Portfolio (BiQAP) will remain focused purely on our top biotech ideas, while updates for non-BiQAP ideas will be provided (as time allows) in BiQ Chat and through the Weekly Recap.
Selected BiQAP Highlights
- Kyverna (KYTX) will be presenting at MSToronto2026 later this month. The key new detail is durability. Kyverna will present full one-year KYSA-8 data on Oct. 21, and the company says a single dose of miv-cel sustained benefit through 12 months with no high-grade CRS, ICANS or IEC-HS. That supports the one-and-done thesis, but the release has no numbers. Hopefully more detail will be presented at the conference.
The progressive MS update has more valuation upside given the market size, but it’s a small investigator-run study, so we should expect early signals rather than true proof of concept. The nearest hard catalyst is still completion of the SPS BLA, which management now expects this quarter.
https://kyvernatx.gcs-web.com/news-releases/news-release-details/kyverna-therapeutics-present-positive-data-stiff-person-syndrome - Prime Medicine (PRME) announced dosing of the first patient in Wilson Disease, which triggered a run in the share price. Early data from the PM577a program, if positive, would be first-in-human proof-of-concept data for Prime's in-vivo gene-editing platform and a major de-risking event for the pipeline. However, balance sheet concerns remain, so I'm still looking for the company to strengthen its cash position, either through dilution or, preferably, through a non-dilutive licensing agreement.
https://investors.primemedicine.com/news-releases/news-release-details/prime-medicine-announces-first-patient-dosed-global-phase-12 - Telix Pharmaceuticals (TLX) announced that it dosed the first patients with Pixclara, Telix's first-in-class brain imaging drug. The market is largely discounting Pixclara as a smaller indication; however, I think it could surprise investors.
https://ir.telixpharma.com/news-releases/news-release-details/first-patients-dosed-telixs-fda-approved-brain-cancer-imaging - Wave Life Sciences (WVE) announced FDA alignment on a biomarker-based registrational path for WVE-006 to treat AATD. The company plans a single, two-year registrational trial, with a one-year interim analysis for potential accelerated approval. I see this as a major derisking event for the WVE-006 program; however, the market barely reacted. The next key catalyst for WVE-006 will be data from the 600mg cohort, expected in Q4.
https://ir.wavelifesciences.com/news-releases/news-release-details/wave-life-sciences-announces-fda-feedback-supports
Selected Non-BiQAP Highlights
- AbCellera Biologics (ABCL) will announce new multiple ascending dose (MAD) data and patient-reported outcomes for ABCL635 at TMS 2026 later this month. Clean repeat-dose safety, especially on liver signals given Veozah’s boxed warning, would support the long-acting antibody thesis. Strong patient-reported outcomes, such as sleep and quality-of-life measures, would help argue that infrequent dosing improves how patients actually feel.
AbCellera Biologics Inc. - AbCellera Announces Presentation of Phase 1/2 Data for ABCL635 at TMS 2026 Annual Meeting - Broadcom (AVGO) will be providing an update on its Ethernet and optics for scale-up networks for large ASIC clusters, where Broadcom directly challenges NVDA's NVLink.
Broadcom Redefines AI Infrastructure with Industry-Leading Networking Innovations at 2026 OCP Global Summit | Broadcom Inc. - Electro Optic Systems (EOPSF) announced an agreement on a A$700M contract for a counter-drone defense system for a Middle Eastern Gulf state. Strategically, this is the first large proof of the MARSS thesis, with EOS as the prime contractor and systems integrator, with MARSS's NiDAR C2 at the core. The contract is still conditional on certain performance requirements, but it strengthens the thesis.
https://investorhub.eos-aus.com/announcements/7779026 - Transocean (RIG) announced partner approval for the Equinor agreement, moving $1B to the confirmed backlog. The company also announced an additional $62M in confirmed backlog with Shell. While this doesn't change much for the stock, it helps firm up cash flow expectations and supports continued demand for the company's harsh-environment rigs in Norway.
Transocean Ltd. Announces Contract Backlog of Approximately $1.1 Billion, Including Fully Approved Equinor Agreement | Transocean Ltd. - SpaceX (SPCX) made a major announcement this past week about purchasing 14MHz of paired spectrum in the 800MHz band from Grain. The market took this as confirmation of SpaceX's plan to become an MNO and compete directly with the AT&T, Verizon, T-Mobile oligopoly. The news triggered a selloff in shares for all three companies, as well as some non-US MNOs. It also triggered a run in tower companies' shares. I think the news is interesting, but was largely expected. I also think the market reaction may have run too far in both directions. (See the Paid Member Section for a more detailed discussion.)
- Zeta Global (ZETA) shares ran this past week on the company's announcement of AthenaOS. I think AthenaOS could be strategically important for the company over the long term; however, I don't see any significant near-term impact on revenue, at least until more details are available about pricing and revenue metrics.
The company also announced plans to develop a custom ASIC with an unnamed semiconductor partner. The market seemed to react well to the news; however, personally, I don't think it makes sense for a company of Zeta's size to develop its own custom ASIC. It remains to be seen whether this was just meant to grab headlines, or whether the company actually plans to devote resources to the project.
Zeta Global Corp - Zeta Live 2026: Zeta Introduces AthenaOS, the Enterprise Intelligence Operating System that Turns Intelligence into Growth
BiQAP Current & Past Performance
Current and past performance for BiQAP portfolio is shown below. To view full portfolio performance (BiQAP and Non-BiQAP), members can click here.


Please note that the BiQ ACB (adjusted cost basis) includes shares and all open options positions, which are accounted for using a "worst case scenario" assumption, plus realized trading profits (and losses) around my core position.
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Paid Member Section
The Paid Member Section includes additional discussion of key topics, portfolio updates, and my trading activity over the past week.